The metabolism of orally administered 4-methyl-2-thiouracil in cockerels

The metabolism of orally administered 4-methyl-2-thiouracil in cockerels.

Hypolipidemic effects of orally administered dextran and cellulose anion exchangers in cockerels and dogs.

Various cellulose and dextran anion exchangers bind bile salts in vitro under conditions of pH and ionic strength resembling those in the lumen of the small intestine. Of these substances, diethylaminoethyl (DEAE) cellulose, guanidoethyl cellulose, and DEAE Sephadex reduced hypercholesterolemia when added to the diet of cholesterol-fed cockerels. In addition, DEAE Sephadex reduced serum sterols...

The determination of 4-methyl-2-thiouracil in animal blood, urine and faces.

Searching for methods for the determination of methylthiouracil in hen's blood, of which in most cases only small quantities are available, we had to simplify the methods described by VAN GENDEREN, VAN LIER AND DE BEUS 1. These methods often take up much time, which may be a serious disadvantage for many experiments. The method finally adopted proved to be sufficiently accurate for our purpose....

Metabolism of orally administered androstenedione in young men.

Androstenedione is a steroid hormone and the major precursor to testosterone. It is available without prescription and taken with the expectation that it will be converted to testosterone endogenously and increase strength and athletic performance. The metabolism of orally administered testosterone has not been well studied. We randomly assigned 37 healthy men to receive 0, 100, or 300 mg oral ...

Metabolism of orally administered cadmium-metallothionein in mice.

The main source of cadmium in the diet is cereal or meat, especially in liver and kidney. Since the cadmium in both liver and kidney is bound to metallothionein, a heat-stable protein, the gastrointestinal absorption and metabolism of cadmium metallothionein (CdMt) was studied in detail. The selective renal cadmium deposition after oral CdMt was analogous to the studies on injected CdMt. Metall...